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来自专栏 Structural Biochemistry · 第 143 篇,共 952 篇

Amino Acids

Proteins have a lot of uses in the body. from cell structure to carrying out reactions. Proteins are in turn made of smaller building blocks called amino acids. There are a total of 20 amino acids.

The 20 Amino Acids

The 20 Amino Acids (Image: Dan Cojocari, CC BY-SA 3.0)

Proteins can be made from a lots of different combinations and number of amino acids. This creates an almost infinite amount of different proteins. Although the sequence of amino acids is a chain, the structure of proteins is far from similar. These amino acids interact with each other to form #D structures. Most common are the alpha helix and the beta strand.

A picture of an alpha helix

A picture of an alpha helix (Image: Zsolt Bikadi / en:User:Bikadi, CC BY-SA 3.0)

Amino acids interacting to make a beta strand

Amino acids interacting to make a beta strand (Image: Fvasconcellos, Public domain)

Although it is possible to determine the 3D structure of a protein, it is not quite possible to predict protein structure from the amino acid chain. This is quite important because diseases such as Alzheimer's and Mad Cow Disease are thought to come from a misfolding of proteins. [1]

References

  • ↑ The Structures of Life, NIH Publication No. 07-2778

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