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Recommendations for Ages 19 Years or Older, United States, 2025

Purpose

Guide health care providers in determining recommended vaccines for specific medical or other indications.

How to use the schedule

Vaccines in the Adult Immunization Schedule

To make vaccination recommendations, healthcare providers should:

  • Determine recommended vaccine by age (Table 1 - By Age)
  • Assess need for additional recommended vaccinations by medical condition or other indication (Table 2 - By Medical Condition)
  • Review vaccine types, dosing frequencies and intervals, and considerations for special situations (Notes)
  • Review contraindications and precautions for vaccine types (Appendix)
  • Review new or updated ACIP guidance (Addendum)

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Download the Schedule

Compliant version of the schedule

Ages 19 Years or Older

Legend

VaccinePregnancyImmuno-compromised (excluding HIV infection)HIV infection CD4 percentage and countMen who have sex with menAsplenia, complement deficiencyHeart or lung diseaseKidney failure, End-stage renal disease or on dialysisChronic liver disease; alcoholism aDiabetesHealth care Personnel b
<15% or <200/mm 3≥15% and ≥200/mm 3

| | See Notes | | | | | | | | |
| Influenza inactivated Influenza recombinant

| | Solid organ transplant (See Notes ) | 1 dose annually | | | | | | | |
| LAIV3

| | 1 dose annually if age 19–49 years | | 1 dose annually if age 19– | 49 years | | | | | |
| RSV

| Seasonal administration. (See Notes ) | See Notes | | See Notes | Liver disease (See Notes ) | See Notes | | | | |
| Tdap or Td

| Tdap: 1 dose each pregnancy | 1 dose Tdap, then Td or Tdap booster every 10 yrs | | | | | | | | |
| MMR

| * | | | | | | | | | |
| VAR

| * | | See Notes | | | | | | | |
| RZV

| | See Notes | | | | | | | | |
| HPV

| * | 3-dose series if indicated | | | | | | | | |
| Pneumococcal

| | | | | | | | | | |
| HepA

| | | | | | | | | | |
| HepB

| See Notes | | | | | | | | | |
| Age ≥ 60 years | | | | | | | | | | |
| MenACWY

| | | | | | | | | | |
| MenB

| | | | | | | | | | |
| Hib

| | HSCT: 3 doses c | | Asplenia: 1 dose | | | | | | |
| Mpox

| See Notes | | See Notes | | See Notes | | | | | |
| IPV

| | Complete 3-dose series if incompletely vaccinated. Self–report of previous doses acceptable (See Notes ) | | | | | | | | |

  • Precaution for LAIV4 does not apply to alcoholism.
  • See notes for influenza; hepatitis B; measles, mumps, and rubella; and varicella vaccinations.
  • Hematopoietic stem cell transplant.

To make vaccination recommendations, healthcare providers should:

  • Determine recommended vaccine by age (Table 1 - By Age)
  • Assess need for additional recommended vaccinations by medical condition or other indication (Table 2 - By Medical Condition)
  • Review vaccine types, dosing frequencies and intervals, and considerations for special situations (Notes)
  • Review contraindications and precautions for vaccine types (Appendix)
  • Review new or updated ACIP guidance (Addendum)

Additional Information

Report

  • Suspected cases of reportable vaccine-preventable diseases or outbreaks to your state or local health department
  • Clinically significant adverse events to the Vaccine Adverse Event Reporting System (VAERS) at www.vaers.hhs.gov or (800-822-7967)

Questions or comments
Contact www.cdc.gov/cdc-info or 800-CDC-INFO (800-232-4636), in English or Spanish, 8 a.m.–8 p.m. ET, Monday through Friday, excluding holidays.

Helpful information

Where this page came from

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