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Prader-Willi syndrome (PWS) is a rare genetic disorder that causes:
- poor muscle tone;
- low levels of sex hormones;
- a constant feeling of hunger.
The part of the brain that controls feelings of hunger and fullness doesn't work properly, so people with PWS overeat, leading to obesity.
Signs
In babies: usually floppy, with poor muscle tone and trouble sucking. Boys may have undescended testicles.
Later:
- short stature;
- poor motor skills;
- weight gain;
- underdeveloped sex organs;
- mild intellectual and learning disabilities.
Treatment
There is no cure. Growth hormone, exercise and supervised diet help build muscle and control weight; other treatments may include sex hormones and behavior therapy. Most people with PWS need specialized care and supervision throughout life.
Sources
Based on "Prader-Willi Syndrome," MedlinePlus, U.S. National Library of Medicine, drawing on the NIH National Institute of Child Health and Human Development; a work of the United States government in the public domain.
Licens: CC0 1.0 (offentligt eje) · Bearbejdet efter medlineplus.gov
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