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**Household contacts of people with pulmonary tuberculosis are at increased
risk of infection and disease**, and the honest starting point of this report
is that **effective interventions to improve case finding and increase the use
of preventive treatment are lacking.**

A pilot project at six health facilities in Uganda tried a package.

What it produced

Index patients with TB disease enrolled521
Household contacts identified1,913
Screened for TB90.9%
Started preventive treatment1,239
Completed itapproximately 95%
New TB cases diagnosed80

Ninety-five per cent completion of a months-long preventive course is a
remarkable number for any health system.

What was in the package

  • Home visits
  • Chest radiography
  • Adherence counselling
  • Travel reimbursements

The fourth item is the one worth pausing on. Three of these are clinical; one
is money for a bus fare.

Preventive TB treatment fails at the point where a well person, with no
symptoms, has to keep travelling to a clinic for months to take medicine for a
disease they do not have. The cost of getting there is not a minor
inconvenience in that calculation — it is often the whole of it.

Including travel reimbursement in the intervention treats the barrier as what
it actually is, and the 95% completion rate is the result.

Why it matters beyond Uganda

Progression from untreated latent infection to disease is how most TB cases
happen. **Global scale-up of this household contact approach might help reach
global TB elimination goals** — and the 80 new cases found among contacts show
the case-finding half working alongside the prevention half.

*Source: Mudoola D, Thekkur P, Nsonga J, et al. Case Finding Among and
Comprehensive Management of Household Contacts of Persons with Pulmonary
Tuberculosis: a Pilot Project — Uganda, 2023–2024. MMWR, Centers for Disease
Control and Prevention.*

Lizenz: CC0 1.0 (gemeinfrei) · Bearbeitet nach www.cdc.gov

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