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Bone marrow is the spongy tissue inside some bones, such as the hip and thigh bones. It holds stem cells, which can develop into:

  • red blood cells, which carry oxygen round the body;
  • white blood cells, which fight infection;
  • platelets, which help blood clot.

What goes wrong

In bone marrow disease, something is wrong with the stem cells or how they develop:

DiseaseWhat happens
Leukaemia, a blood cancerthe marrow makes abnormal white blood cells
Aplastic anaemiathe marrow doesn't make red blood cells
Myeloproliferative disordersthe marrow makes too many white blood cells
Other diseases, such as lymphomaspread into the marrow and affect blood-cell production

Causes include genetics and environmental factors.

Tests and treatment

  • Tests include blood tests and bone marrow tests.
  • Treatment depends on the disorder and how severe it is, and may involve medicines, blood transfusions or a bone marrow transplant.

Sources

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Licence: CC0 1.0 (public domain) · Adapted from medlineplus.gov

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