Tetrahydrocannabinol Intoxication from Food at a Restaurant — Wisconsin, October 2024

Amanda Kita-Yarbro, MPH1; Stefanie Moccero1; Katie Brobston, MS1; Jacob Goebel1; Janice Block Banks1; Christy Vogt, MPH1; Casey Schumann, MS1; Katarina M. Grande, MPH1; Julia Olsen, MSEd1; Bonnie Armstrong, MPH1 (

Summary

What is already known about this topic?

Tetrahydrocannabinol (THC), a psychoactive substance found in Cannabis sativa plants, including varieties such as hemp, is increasingly being used in consumer products.

What is added by this report?

During October 22–24, 2024, at least 85 persons, ranging from age 1–91 years, ate food from a restaurant in Wisconsin and experienced symptoms consistent with THC intoxication. The restaurant was in a building with a cooperative (i.e., shared) kitchen used by a state-licensed vendor who produced edible THC products. The restaurant mistakenly used THC-infused oil from the cooperative kitchen to prepare dough.

What are the implications for public health practice?

Clinicians and public health practitioners should be alert to the possibility of mass THC intoxication events via food.

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Abstract

Tetrahydrocannabinol (THC), a psychoactive substance found in Cannabis sativa plants, including varieties such as hemp, is increasingly being used in consumer products. On October 24, 2024, local emergency medical services reported to Public Health Madison & Dane County (PHMDC) in Wisconsin that since October 22, they had transported seven persons to a local hospital for various symptoms, including dizziness, sleepiness, and anxiety. All seven persons reported having recently eaten food from the same local restaurant. Investigation by PHMDC determined that on October 22, the restaurant had run out of cooking oil and used oil from a cooperative (i.e., shared) kitchen located in the same building. One of the vendors who used the kitchen made edible products using hemp-derived Δ9-THC. On October 24, PHMDC posted a food and symptom history questionnaire on its website and shared the link via press release and social media. Among 107 responses that were considered valid, 85 persons met the following case definition of THC intoxication: 1) ate pizza, garlic bread, cheese bread, or a grinder (submarine sandwich) purchased from the restaurant during October 22–24 and 2) reported at least one symptom of THC intoxication that began within 5 hours after eating the restaurant’s food, defined as dizziness, sleepiness, anxiety, short term memory impact or time distortion, increased heart rate, nausea, paranoia, panic attack, increased blood pressure, vomiting, or hallucinations. Clinicians and public health practitioners should be alert to the possibility of mass THC intoxication events via food. Health care providers, public health professionals, and emergency responders should consider THC intoxication in persons with sudden onset of symptoms such as dizziness, sleepiness, anxiety, altered reality perception, increased heart rate, nausea, or other symptoms of THC ingestion. Regulations regarding practices such as standard, clear labeling and locked storage for ingredients containing THC, might decrease the risk for unintentional THC exposure at licensed food businesses.

Investigation and Results

Tetrahydrocannabinol (THC) is a psychoactive substance found in Cannabis sativa plants, including varieties such as hemp; concentrations are lower in the hemp plant. On October 24, 2024, local emergency medical services reported to Public Health Madison & Dane County (PHMDC) in Wisconsin that since October 22, they had transported seven persons to a local hospital for various symptoms, including dizziness, sleepiness, and anxiety. All seven persons reported having recently eaten food from the same local restaurant. Emergency services conducted carbon monoxide testing in two residences of symptomatic persons and at the restaurant, and the test results were negative. The seven persons who were transported were treated in the emergency department (ED) of a Stoughton, Wisconsin hospital with symptoms of THC intoxication. Later that day, one of the ED patients, who had eaten pizza from the restaurant the previous day (October 23), contacted PHMDC at the suggestion of the hospital and reported receiving a positive THC test result without having knowingly consumed THC. PHMDC initiated an outbreak investigation. This investigation was determined by PHMDC to be nonresearch public health surveillance and therefore did not require institutional review board review.

On October 24, PHMDC contacted the restaurant owner. The owner was aware of the illnesses and agreed to close immediately. The same day, the restaurant owner called PHMDC and reported that a state-licensed business in a cooperative (i.e., shared) kitchen in the same building as the restaurant made edible products using hemp-derived Δ9-THC. The vendor infused cooking oil on-site with hemp-derived THC. Because of the possible THC involvement, PHMDC notified local police. During a third call with PHMDC, the restaurant owner reported that on October 22, the restaurant had run out of cooking oil and used oil from the cooperative kitchen to prepare dough that was served during October 22–24. The owner initially thought the oil was plain canola oil but later realized it might have been infused with THC. Oil from a large, labeled storage container (

Public Health Response

On October 24, PHMDC posted a food and symptom history questionnaire on its website. The link was distributed widely through a press release and on social media. All persons who experienced symptoms after eating food from the restaurant during October 22–24 were asked to complete the questionnaire. Respondents were asked to provide the names of other persons who had eaten food from the restaurant and become ill. The hospital provided PHMDC with the names of nine patients who sought care during October 23–24 after eating at the restaurant. On October 25, PHMDC contacted persons on this list who had not completed a questionnaire and asked them to complete the questionnaire.

During October 24–30, PHMDC received 208 responses; 101 were excluded from analysis because they contained 1) mostly incomplete information, 2) the name of a fictional character, 3) names or addresses that included marijuana or THC-related words, or 4) information that indicated the person did not actually eat food from the restaurant. The remaining 107 responses were considered valid (

On October 24, PHMDC issued a press release alerting the public via social media not to eat leftover pizza purchased from the restaurant during October 22–24. This information was updated on October 28 to include leftover grinders, garlic bread, and cheese bread. The updated information was shared with the public via social media and PHMDC’s blog, which is posted to the PHMDC website and emailed to approximately 3,000 subscribers.

Discussion

Eighty-five persons who responded to a health department questionnaire reported symptoms consistent with THC intoxication that occurred within 5 hours after eating food from a pizza restaurant, including 15 who received a positive THC test result. Respondents were asked to provide the names of others who ate food from the restaurant and became ill, which identified eight additional ill persons. No leftover foods were tested for THC, no quantitative testing was performed on the oil, and no analytical study (e.g., case-control study) was conducted.

Although FDA has not found that any use of a cannabinoid, including THC, in food would be safe and lawful under the Federal Food, Drug, and Cosmetic Act,†** **these products can be found in adult cannabis and hemp marketplaces, some of which seek to follow state, territorial, or tribal laws regarding their use. Increased availability of food items containing THC increases the possibility that children (1,2) and adults (3) might unknowingly consume these items and experience symptoms that lead them to seek medical care. Co-location of food establishments with businesses that make THC-infused products increases the risk that a THC-containing ingredient might be added to food, either intentionally or unintentionally. Health care providers, public health professionals, and emergency responders should consider THC intoxication in persons with sudden onset of symptoms such as dizziness, sleepiness, anxiety, altered reality perception, increased heart rate, nausea, or other symptoms of THC ingestion. Regulations regarding practices such as standard, clear labeling (4) and locked storage for ingredients containing THC, might decrease the risk for unintentional THC exposure at licensed food businesses.

Acknowledgments

Persons who completed an outbreak questionnaire; Pema Choden, Morgan Finke, Brittany Grogan, Shoua Herr, Jeff Lafferty, Rebecca LeBeau, Nicole Morales, Myranda Phelps-McGuire, Ryan Sheahan, Leslie Walker, Cristina Wills, Alyssa Yuknis, Public Health Madison & Dane County; Stoughton Area Emergency Medical Services; Stoughton Fire Department; Stoughton Hospital; Stoughton Police Department.

Corresponding author: Amanda Kita-Yarbro, akita@publichealthmdc.com.

1Public Health Madison & Dane County, Madison, Wisconsin.

All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.

• Wisconsin Food Code | Agriculture, Trade and Consumer Protection | ATCP 75 Appendix

† Food and Drug Administration | Warning Letter | Latro Inc. – 698196 – 03/25/2025; Food and Drug Administration | Warning Letter | Mary Jane’s Bakery Co. LLC – 678010 – 07/15/2024; Food and Drug Administration | Warning Letter | Earthly Hemps – 674916 – 07/15/2024

References

• Food and Drug Administration. FDA warns consumers about the accidental ingestion by children of food products containing THC. Silver Spring, MD: US Department of Health and Human Services, Food and Drug Administration; 2022. https://www.fda.gov/food/alerts-advisories-safety-information/fda-warns-consumers-about-accidental-ingestion-children-food-products-containing-thc
• Thomas AA, Mazor S. Unintentional marijuana exposure presenting as altered mental status in the pediatric emergency department: a case series. J Emerg Med 2017;53:e119–23. https://doi.org/10.1016/j.jemermed.2017.08.007 PMID:28987305
• Fong K, Hsueh A, Kendric K, et al. Unwitting adult marijuana poisoning: a case series. Clin Toxicol (Phila) 2021;59:913–7. https://doi.org/10.1080/15563650.2021.1891241 PMID:33688774
• Soroosh AJ, Henderson R, Dodson L, Mitchell CS, Fahey JW. Mitigating potential public health problems associated with edible cannabis products through adequate regulation: a landscape analysis. Crit Rev Food Sci Nutr 2020;61:3091–99. https://doi.org/10.1080/10408398.2020.1793099 PMID:32791846

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Photo/Public Health Madison & Dane County

Abbreviation: D9 = Δ9-tetrahydrocannabinol.

• Containers are labeled as D9 oil, with the type of oil unclear.

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Abbreviations: DATCP = Wisconsin Department of Agriculture, Trade and Consumer Protection; PHMDC = Public Health Madison & Dane County; THC = tetrahydrocannabinol.

† Examples of terms used by respondents to describe ataxia included loss of balance; unable to stand, walk, or move; and feeling unsteady.
§ Examples of terms used by respondents to describe perception distortion included false sense of reality, psychosis, felt like being in a dream, heightened hearing, and having an out-of-body experience.

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