How often does COVID-19 spread inside a home, and how fast? Earlier estimates varied widely, and there was little data on spread from children. A CDC-supported study in Nashville, Tennessee, and Marshfield, Wisconsin, followed households closely from April to September 2020.
How the study worked
- The index patient was the first person in a household with COVID-19–like symptoms and a positive RT-PCR test, living with at least one other person.
- Households joined within 7 days of the index patient's illness; the median index patient was enrolled 4 days after getting sick.
- Everyone kept symptom diaries and collected their own nasal swabs (and sometimes saliva) daily; the first 7 days of samples were tested.
The analysis covered 101 households — 101 index patients and 191 household members who had no symptoms when the index patient fell ill. Index patients' median age was 32 (range 4–76); 14 were under 18.
Contact was close: 69% of index patients spent more than 4 hours in the same room as someone else the day before they got sick, and 40% shared a bedroom before their illness began.
What it found
| Share of household members infected within 7 days | |
|---|---|
| Nasal or saliva samples | 53% (102 of 191) |
| Nasal swabs only | 47% |
| Excluding 54 already positive at enrollment | 35% |
| Index patient under 12 | 53% |
| Index patient 12–17 | 38% |
- About 75% of infections were found within 5 days of the index patient's first symptoms.
- Spread was high in every racial and ethnic group, and substantial whether the index patient was a child or an adult.
- Only 40% of infected household members had symptoms when first found positive; over the week, 67% reported symptoms — so many infections were silent, underscoring the need for quarantine.
These rates were higher than many earlier estimates, perhaps because of this study's daily testing — or because studies elsewhere isolated patients outside the home or used masks more at home.
What to do
Because household spread is common and fast:
- Isolate right away — at the first symptoms, when you're tested after a high-risk exposure, or on a positive test, whichever comes first — rather than waiting for results. Stay home and use a separate bedroom and bathroom if you can.
- Everyone in the home, including the sick person, should wear a mask in shared spaces.
- Household contacts should quarantine as much as possible, stay away from people at high risk, and get tested.
Catching infections before symptoms would take frequent, fast community testing; the study aims to inform when and how often to test.
Limits: others may have been infected at the same time as the index patient; some infections may have come from outside the home; samples were self-collected; and the families may not represent the U.S. population.
Sources
Based on Carlos G. Grijalva, Melissa A. Rolfes, Yuwei Zhu and colleagues, "Transmission of SARS-COV-2 Infections in Households — Tennessee and Wisconsin, April–September 2020," MMWR, volume 69, Centers for Disease Control and Prevention; a work of the United States government in the public domain.
许可协议: CC0 1.0(公有领域) · 改编自 www.cdc.gov
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