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Lymphoma is a cancer of the lymph system, part of the body's immune system. There are many types. One is Hodgkin disease; all the others are called non-Hodgkin lymphomas.

Non-Hodgkin lymphoma

Non-Hodgkin lymphoma begins when a type of white blood cell — a T cell or B cell — becomes abnormal and divides over and over, making more abnormal cells that can spread to almost any other part of the body. Usually, doctors don't know why a person develops it, but the risk is higher for people with a weakened immune system or certain infections.

Symptoms

Non-Hodgkin lymphoma can cause many symptoms, including:

  • swollen, painless lymph nodes in the neck, armpits or groin;
  • unexplained weight loss;
  • fever;
  • drenching night sweats;
  • coughing, trouble breathing or chest pain;
  • weakness and tiredness that don't go away;
  • pain, swelling or a feeling of fullness in the abdomen.

Diagnosis

Doctors diagnose lymphoma with a physical exam, blood tests, a chest x-ray and a biopsy.

Treatment

Treatments include:

  • chemotherapy;
  • radiation therapy;
  • targeted therapy, which uses drugs or other substances to attack specific cancer cells while doing less harm to normal cells;
  • biologic therapy, which boosts the body's own ability to fight cancer;
  • therapy to remove proteins from the blood.

People without symptoms may not need treatment right away; instead, doctors may monitor them closely, an approach called watchful waiting.

Sources

  • MedlinePlus, National Library of Medicine: "Lymphoma," with information from the National Cancer Institute, National Institutes of Health.
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Licence: CC0 1.0 (public domain) · Adapted from medlineplus.gov

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